- Why is prostate cancer osteoblastic (i.e. most cancers when they spread to bone result in bone resorption (i.e., osteolytic); whereas, prostate cancer results in bone production (i.e. osteoblastic).
- Why does prostate cancer preferentially metastasize to bone as opposed to other sites.
- How can we successfully treat metastases that are highly heterogenous (i.e within one patient, different metastases have different properties).
Tuesday, September 28, 2010
Evan Keller, University of Michigan