Tuesday, September 28, 2010

Evan Keller, University of Michigan

Three Problems:
  • Why is prostate cancer osteoblastic (i.e. most cancers when they spread to bone result in bone resorption (i.e., osteolytic); whereas, prostate cancer results in bone production (i.e. osteoblastic).
  • Why does prostate cancer preferentially metastasize to bone as opposed to other sites.
  • How can we successfully treat metastases that are highly heterogenous (i.e  within one patient, different metastases have different properties).
Background Papers:

No comments:

Post a Comment