Physics of Cancer Metastasis

November 1-2, 2010. A site for posting meeting information, cancer researcher's top three problems in the understanding and treatment of metastatic cancer and links to their selected papers (1-3).

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Thursday, September 23, 2010

Gary Stein, University of Massachusetts

Three Problems:
  • Epigenetic control in tumorigenesis, tumor progression and metastasis 1
  • Nuclear microenvironments in biological control and cancer 2
  • Cell adhesion and motility in tumor progression 3

References:

1Zaidi SK, Young DW, Montecino M, Lian JB, van Wijnen AJ, Stein JL, Stein GS. (2010) Mitotic bookmarking of genes: a novel dimension to epigenetic control. Nature Reviews Genetics Aug;11(8):583-9. Epub 2010 Jul 13.

2Zaidi SK, Young DW, Javed A, Pratap J, Montecino M, van Wijnen AJ, Lian JB, Stein JL, Stein GS   (2007) Nuclear microenvironments in biological control and cancer.  Nature Reviews Cancer, 7:454-463.

3Altieri DC, Languino LR, Lian JB, Stein JL, Leav I, van Wijnen AJ, Jiang Z, Stein GS. Article.  (2009) Prostate cancer regulatory networks. J Cell Biochem. Aug 1;107(5):845-52.
Posted by Sara Bradley at 3:15 PM
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Meeting Coordinator

Sara Bradley
sara.bradley@comcast.net
703-963-1326

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  • ▼  2010 (17)
    • ►  October (8)
    • ▼  September (9)
      • Evan Keller, University of Michigan
      • Robert Getzenberg, Johns Hopkins University
      • Don Coffey, Johns Hopkins University
      • Gary Stein, University of Massachusetts
      • Lance Munn, Harvard
      • Yibin Kang, Princeton
      • Ken Pienta, University of Michigan
      • Meeting Logistics
      • Physics of Cancer Metastasis

To All,

This preparation seems to be moving nicely. Actually I think that most questions can be answered by my "trivial dream idea": if one can label every different, in any respect, cancer cell with a different color and follow its time history then we would know everything we would like to know. Well thanks God this is impossible, otherwise there would be no science. So now our goal is to shift the questions to addressing what is measurable and what not in biology and what can be inferred by theory and experiment. We are where physics excels!

Thanks for the great input.
Krastan

Krastan Blagoev, NSF

Physics of Cancer Metastasis

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